OxyContin vs Oxycodone: What Is the Difference?

OxyContin vs Oxycodone — Key Differences

Both OxyContin and oxycodone contain the same opioid compound, but they differ significantly in formulation and duration of action.

What Is Oxycodone?

Oxycodone is a semi-synthetic opioid analgesic derived from thebaine. It binds to mu, kappa and delta opioid receptors in the brain and spinal cord, reducing the perception of pain and producing a sense of wellbeing.

What Is OxyContin?

OxyContin is the extended-release (ER) formulation of oxycodone. Its patented matrix delivers oxycodone over a 12-hour period, making it suitable for around-the-clock management of moderate to severe chronic pain in opioid-tolerant patients.

Endone (Australia)

In Australia, Endone is the most common brand of immediate-release oxycodone. Available in 5 mg tablets, it is commonly prescribed for post-operative pain, cancer pain and severe acute pain.

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